Title : Implementation and Evaluation of Simultaneous Video - Electroencephalography ( Video - EEG ) and functional Magnetic Resonance Imaging (

The objective of this study is to demonstrate that the addition of video to EEG-correlated fMRI for simultaneous recording can be done efficiently. We investigated the effect of placing EEG, video equipment and their required power supplies inside the scanner room, on EEG, video and MRI data quality, and evaluated video-EEG-fMRI by modelling a hand motor task. Gradient-echo echo-planner images (EPI) were acquired on a 3T MRI scanner at variable camera positions in a test object (with and without radiofrequency amplification), and human subjects. EEG was recorded using a commercial MR-compatible 64-channel cap and amplifiers. Video recording was performed using a two-camera custom-made system with EEG synchronization. An in-house script was used to calculate signal to fluctuation noise ratio (SFNR) from raw EPI, and the results compared in data from human subjects with and without concurrent video recording. Five subjects were investigated with video-EEGfMRI while performing hand motor task. The fMRI time series data was analysed using statistical parametric mapping based on the paradigm-prescribed block design and on an alternative video based block design. Introduction of the cameras did not alter the SFNR substantially in the test object and human subjects. Video and EEG quality assessed by two expert observers also did not show any significant artefact. The SPM{T} maps from video based general linear models revealed additional BOLD responses in the expected locations for noncompliant subjects with the paradigm design. We conclude that video-EEG-fMRI set up can be implemented without affecting the data quality significantly and may provide valuable information on actual behaviour that may be used for the analysis of fMRI data.